After completing his graduation in Law, Jatti began his legal practice as an advocate for a very short span of time in his home town Jamkhandi. In 1940, he entered politics as a Municipality member at Jamkhandi and subsequently became the President of the Jamkhandi Town Municipality in 1945. Finally he became the ‘dewan’ of Jamkhandi state in 1948.
Jatti was appointed as the Lieutenant Governor of Pondicherry in 1968. He became the Governor of Odisha in 1972 and, in 1974. He assumed office as the fifth Vice-President of India. He became acting President for a brief period after the death of Fakhruddin Ali Ahmed in 1977
Jatti died on 7 June, 2002 at the age of 89. The soft-spoken Jatti rose from a humble beginning as a Municipality member to India’s second-highest office during a five-decade-long chequered political career. He completed his obligations with the constitutional dignity.